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When local vasoconstriction becomes excessive, the body responds by releasing specific neuropeptides (CGRP, substance P, and neurokinin A), causing a rebound dilation in the segments of these overly constricted arteries. This sudden rebound dilation is a natural defensive mechanism of our body to compensate for extended periods of blood deprivation. These arteries are wrapped with sensitive pain receptors and are being activated due to dilation of arteries, thus causing migraine pain. The migraine pain is often localized because over-dilation occurs in a limited area.You do not need directions or knowledge of medical doctors. Apparatus for home treatment Medicomat everything works itself automatically - the examinations and then carries out the modern treatment of acupuncture without needles, without pain. Treating poor circulation, high blood pressure, headache, migraine, depression, dizziness, rheumatism, spondylosis, sciatica, insomnia.

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The lack of energy associated with tiredness can sometimes cause difficulty with normal daily activities, leading to problems with attentiveness and concentration. Causes of tiredness range from lack of sleep and over exercise to medical and surgical treatments.

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